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Post Doctoral Fellowship, Bioinformatics, Department of Hematology and Oncology

Job ID: 18006

Updated: June 7, 2019

Location: Foothills Campus

Position Description

Duration: Two years with potential for extension pending availability of funding
Start Date: 
As soon as possible
Salary: $50,000 CAD/yr plus benefits       

Job Description:

The Precision Oncology hub, in the Department of Oncology, Cumming School of Medicine at the University of Calgary is accepting applications for a Postdoctoral Fellow with specialization in bioinformatics to support the statistical and bioinformatics aspects of translational research program in the Department of Hematology and Oncology.  The successful candidate will be working in the Precision Oncology Hub at the Tom Baker Cancer Center, under the leadership of the Scientific Director Dr. Paola Neri.  Dr. Neri’s research activities examine the signalling pathways and genomic alterations in cancer cells with the goal of discovering new molecular targets that may be translated into therapeutic applications. Utilizing high-throughput genomics analyses of tissue samples, researchers are developing prognostic biomarkers and signatures that will better stratify cancer patients and inform treatment options to improve disease outcomes.

The bioinformatician will assist cancer investigators with project-specific analyses of data from next-generation sequencing and other molecular analysis platforms, and will contribute expertise and service to research programs that are competitive for funding at the provincial and/or national levels.

The position involves the ability to work independently to develop a strategic plan for bioinformatics research directions, perform complex analyses, analyse and interpret data, provide guidance in experimental design, and contribute to writing research grants leading to the establishment of new programs, reports and scientific manuscripts.  The position requires excellent technical skills and advanced knowledge in the principles, concepts and practices relevant to bioinformatic analyses of genomic data, as well as strong scientific knowledge in related areas.   

Qualifications/Expertise Required:

The ideal candidate will be a recent Ph.D. graduate in either bioinformatics or biostatistics.  In addition, the individual should have:

  • Minimum 2 years experience in translational bioinformatics research developing bioinformatics and biostatistics methods for biomarker discovery
  • Experience in genomics analysis, next generation sequencing and pipeline / database development
  • Knowledge and experience with large scale biological data analyses, especially high-throughput sequencing data
  • Experience working on molecular and genomic analysis of cancer samples in a clinical translational research environment
  • Experience in genomic profiling and bioinformatic analysis of cancer samples
  • Demonstrated development of statistical methods for genotype-phenotype association studies
  • Experience in genome and transcriptome assembly using standard tools, including statistical testing of sequencing uncertainties
  • Demonstrated proficiency in Java, Linux, R, Perl, next-gen sequencing and association mapping bioinformatics tools
  • Working knowledge of annotation databases including GeneCards, Ensmbl, GO, Reactome, SwissPort etc.
  • Experience working in a complex collaborative and multidisciplinary team environment
  • Team oriented with excellent written and verbal communication skills, and demonstrated ability to self-educate in current bioinformatics techniques and resources
  • Strong track record of publications in high impact journals of the field

The postdoctoral fellow will be responsible for the following research activities;

  • Perform bioinformatics processing, data analysis and interpretation of NGS (next generation sequencing) data using appropriate genomics toolsDevelop innovative methods and/or novel applications of existing methodsImplement newly developed pipelines adopted by others in the field
  • Provide bioinformatics expertise in the planning and implementation of research concepts
  • Design and deploy analysis pipeline suitable for each project
  • Optimize analysis parameters including the development of research data standards
  • Work closely with experimental researchers to generate and provide analysis reports, project reports and perform requested custom analysis
  • Assist in writing research proposals for further development of the bioinformatics genomic analysis research program
  • Contribute to scientific manuscripts to be submitted for publication
  • Contribute to grant submissions to provide operational and funding support for the research programs
  • Establish and maintain accurate electronic and paper records regarding laboratory research

Application details:

Applications should be submitted by e-mail to the following contact, with the subject line “Post Doctoral Fellowship, Bioinformatician”.  Please include a cover letter, your academic CV and the names and contact information of a least three external references;

Dr. Paola Neri
e-mail: epneri@ucalgary.ca
Arnie Charbonneau Cancer Institute
Department of Hematology and Oncology
University of Calgary
Mailing Address: Room 350, HMRB
3330 Hospital Drive, NW
Calgary, AB, Canada  T2N 4N1

The application deadline is July 5, 2019.

Additional Information

To learn more about postdoctoral scholar opportunities at the University of Calgary and all we have to offer, view our Postdoc Careers website. For more information about the Cumming School of Medicine visit Careers in the Cumming School of Medicine.

About the University of Calgary

The University of Calgary is Canada’s leading next-generation university – a living, growing and youthful institution that embraces change and opportunity with a can-do attitude. Located in the nation’s most enterprising city, the university is making tremendous progress on its Eyes High journey to be recognized as one of Canada’s top five research universities, grounded in innovative learning and teaching and fully integrated with the community it both serves and leads. The University of Calgary inspires and supports discovery, creativity and innovation across all disciplines. For more information, visit ucalgary.ca.

To succeed as one of Canada’s top universities, where new ideas are created, tested and applied through first-class teaching and research, the University of Calgary needs more of the best minds in our classrooms and labs. We’re increasing our scholarly capacity by investing in people who want to change the world, bringing the best and brightest to Calgary to form a global intellectual hub and achieve advances that matter to everyone.

About Calgary, Alberta

Calgary is one of the world's cleanest cities and has been named one of the world's most livable cities for years. Calgary is a city of leaders – in business, community, philanthropy and volunteerism. Calgarians benefit from the strongest economy in the nation and enjoy more days of sunshine per year than any other major Canadian city. Calgary is less than an hour’s drive from the Rocky Mountains and boasts the most extensive urban pathway and bikeway network in North America.

The University of Calgary recognizes that a diverse staff/faculty benefits and enriches the work, learning and research experiences of the entire campus and greater community. We are committed to removing barriers that have been historically encountered by some people in our society. We strive to recruit individuals who will further enhance our diversity and will support their professional success while they are here. We encourage all qualified applicants to apply, however preference will be given to Canadian citizens and permanent residents of Canada.

 

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